Neural mechanisms of speech motor learning in persons who stutter

Fluent speech production requires rapid coordination among respiratory, laryngeal, and articulatory processes and is mediated by multiple neural systems (Bohland & Guenther, 2006). Stuttering is a fluency disorder characterized by core deficits in speech motor planning. Previous research indicates people who stutter (PWS) exhibit deficits in speech motor sequence learning and are slower and less accurate over practice relative to fluent speakers (Ludlow, Siren, & Zikira, 2004; Namasivayam & VanLieshout, 2004; Smits-Bandstra & De Nil, 2007; Smits-Bandstra, De Nil, & Saint-Cyr, 2006). Furthermore, the neural bases of impaired speech motor sequence learning in PWS are not well understood. We present a study in which PWS (n=18) and persons with fluent speech (PFS) (n=17) were taught phonotactically illegal (e.g. gbesb) and phonotactically legal (e.g. blerk) speech motor sequences over two practice sessions. Functional magnetic resonance imaging (fMRI) was used to investigate brain regions underlying the production of learned illegal syllables and novel illegal syllables. With practice, subjects produced syllables more accurately, which is indicative of motor sequence learning. Our findings suggest a speech motor performance deficit in PWS. Furthermore, these findings indicate speech motor sequence learning relies on a speech motor sequence learning network

Biconed graphs, edge-rooted forests, and h-vectors of matroid complexes

A well-known conjecture of Richard Stanley posits that the $h$-vector of the independence complex of a matroid is a pure ${\mathcal O}$-sequence. The conjecture has been established for various classes but is open for graphic matroids. A biconed graph is a graph with two specified `coning vertices', such that every vertex of the graph is connected to at least one coning vertex. The class of biconed graphs includes coned graphs, Ferrers graphs, and complete multipartite graphs. We study the $h$-vectors of graphic matroids arising from biconed graphs, providing a combinatorial interpretation of their entries in terms of `edge-rooted forests' of the underlying graph. This generalizes constructions of Kook and Lee who studied the M\"obius coinvariant (the last nonzero entry of the $h$-vector) of graphic matroids of complete bipartite graphs. We show that allowing for partially edge-rooted forests gives rise to a pure multicomplex whose face count recovers the $h$-vector, establishing Stanley's conjecture for this class of matroids.Comment: 15 pages, 3 figures; V2: added omitted author to metadat

Exploiting saliency for object segmentation from image level labels

There have been remarkable improvements in the semantic labelling task in the recent years. However, the state of the art methods rely on large-scale pixel-level annotations. This paper studies the problem of training a pixel-wise semantic labeller network from image-level annotations of the present object classes. Recently, it has been shown that high quality seeds indicating discriminative object regions can be obtained from image-level labels. Without additional information, obtaining the full extent of the object is an inherently ill-posed problem due to co-occurrences. We propose using a saliency model as additional information and hereby exploit prior knowledge on the object extent and image statistics. We show how to combine both information sources in order to recover 80% of the fully supervised performance - which is the new state of the art in weakly supervised training for pixel-wise semantic labelling. The code is available at https://goo.gl/KygSeb.Comment: CVPR 201

The role of the insula in speech and language processing

Lesion and neuroimaging studies indicate that the insula mediates motor aspects of speech production, specifically, articulatory control. Although it has direct connections to Broca\u27s area, the canonical speech production region, the insula is also broadly connected with other speech and language centres, and may play a role in coordinating higher-order cognitive aspects of speech and language production. The extent of the insula\u27s involvement in speech and language processing was assessed using the Activation Likelihood Estimation (ALE) method. Meta-analyses of 42 fMRI studies with healthy adults were performed, comparing insula activation during performance of language (expressive and receptive) and speech (production and perception) tasks. Both tasks activated bilateral anterior insulae. However, speech perception tasks preferentially activated the left dorsal mid-insula, whereas expressive language tasks activated left ventral mid-insula. Results suggest distinct regions of the mid-insula play different roles in speech and language processing. © 2014 Elsevier Inc

The Chemical Compositions of Very Metal-Poor Stars HD 122563 and HD 140283; A View From the Infrared

From high resolution (R = 45,000), high signal-to-noise (S/N > 400) spectra gathered with the Immersion Grating Infrared Spectrograph (IGRINS) in the H and K photometric bands, we have derived elemental abundances of two bright, well-known metal-poor halo stars: the red giant HD 122563 and the subgiant HD 140283. Since these stars have metallicities approaching [Fe/H] = -3, their absorption features are generally very weak. Neutral-species lines of Mg, Si, S and Ca are detectable, as well as those of the light odd-Z elements Na and Al. The derived IR-based abundances agree with those obtained from optical-wavelength spectra. For Mg and Si the abundances from the infrared transitions are improvements to those derived from shorter wavelength data. Many useful OH and CO lines can be detected in the IGRINS HD 122563 spectrum, from which derived O and C abundances are consistent to those obtained from the traditional [O I] and CH features. IGRINS high resolutions H- and K-band spectroscopy offers promising ways to determine more reliable abundances for additional metal-poor stars whose optical features are either not detectable, or too weak, or are based on lines with analytical difficulties.Comment: Accepted for publication in ApJ (28 pages, 4 tables, 6 figures

Compositional Synthesis via a Convex Parameterization of Assume-Guarantee Contracts

We develop an assume-guarantee framework for control of large scale linear (time-varying) systems from finite-time reach and avoid or infinite-time invariance specifications. The contracts describe the admissible set of states and controls for individual subsystems. A set of contracts compose correctly if mutual assumptions and guarantees match in a way that we formalize. We propose a rich parameterization of contracts such that the set of parameters that compose correctly is convex. Moreover, we design a potential function of parameters that describes the distance of contracts from a correct composition. Thus, the verification and synthesis for the aggregate system are broken to solving small convex programs for individual subsystems, where correctness is ultimately achieved in a compositional way. Illustrative examples demonstrate the scalability of our method

During the COVID-19 Pandemic, Lung Specialists of the World Implore You: Inhale Only Clean Air

Recent social media and lay news report that nicotine may help protect from COVID-19. However, lung specialists of the American Thoracic Society and California Thoracic Society recommend that you inhale only clean air. Research shows that exposure to smoke, vapors, and air pollution all contribute to worse outcomes in COVID-19 infection. This fact sheet summarizes some of the common public questions addressed to lung healthcare professionals

The Student Movement Volume 107 Issue 23: So Long, Farewell: Students Step Into the Future

HUMANS Advice to Younger Selves, Interviewed by: Anna Pak Finals Stress Management, Gloria Oh Farewell to Pastor Dwight Nelson, Student Movement Staff What does AANHPI Heritage Month Mean?, Grace No ARTS & ENTERTAINMENT Currently: Reflecting on the Original Script, Solana Campbell In Memory of K.V. Rathnam, Ysabelle Fernando The Deal Premiers at Sonscreen Film Festival, Solana Campbell Through Their Eyes: AANHPI Expression, Amelia Stefanescu NEWS A Night at AU: SASA Cultural Night, Solana Campbell Interview with Professor Daniel Weber: Envision Magazine, Interviewed By: Brendan Oh Interview with Gloria Oh: Transforming an Idea into Reality, Interviewed By: Brendan Oh IDEAS All at Once: How AANHPI Media Representation Took Over 2023, Bella Hamann Raise A Glass to Freedom?, Terika Williams The Gem Off the Back of a Lorry, Gabi Francisco PULSE Goodbye and Welcome: Letters to the Incoming and Outgoing Presidents, The Andrews University Student Association Senate Honduras Mission, Interviewed By: Abraham Bravo Last Words for the School Year, Elizabeth Dovich In Summer: Professor Olaf Presents You the Ultimate Way to Spend Summer, Gloria Oh LAST WORD Take it from Me Part II, The Student Movement Staffhttps://digitalcommons.andrews.edu/sm-107/1022/thumbnail.jp